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Article

Immortalized Human Dorsal Root Ganglion Cells Differentiate into Neurons with Nociceptive Properties

1 Jul 1999

Abstract excerpt

A renewable source of human sensory neurons would greatly facilitate basic research and drug development. We had established previously conditionally immortalized human CNS cell lines that can differentiate into functional neurons (). We report here the development of an immortalized human dorsal root ganglion (DRG) clonal cell line, HD10.6, with a tetracycline-regulatable v-myc oncogene. In the proliferative...

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PMID: 10377351
DOI: 10.1523/jneurosci.19-13-05420.1999

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