Article

Improvements in Weight, Eating-Disorder Symptoms and Sleep Following Off-Label Leptin Treatment in an Adolescent with Chronic Anorexia Nervosa and Insomnia: A Case Report

2026-07-08

Abstract excerpt

<title>Abstract</title> <p>We report off-label administration of human recombinant leptin (metreleptin) over a 12-day period in a 17-year-old female adolescent with chronic anorexia nervosa (AN) and clinically significant insomnia. Two observation windows are distinguished throughout: a short-term window between day 1 (pre) and day 12 (post) of dosing, and a longer-term window between day 12 and the two-month fol...

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Literature Corpus work: 0999d294-587d-50be-bb82-46bebff89c59
DOI: 10.21203/rs.3.rs-10142617/v1

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