Article

The N-terminus of GPR37L1 is proteolytically processed by matrix metalloproteases

2020-06-28

Abstract excerpt

GPR37L1 is an orphan G protein-coupled receptor expressed exclusively in the brain and linked to seizures, neuroprotection and cardiovascular disease. Based upon the observation that fragments of the GPR37L1 N-terminus are found in human cerebrospinal fluid, we hypothesized that GPR37L1 was subject to post-translational modification. Heterologous expression of GPR37L1-eYFP in either HEK293 or U87 glioblastoma cell...

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Literature Corpus work: 097a29cb-e07b-59b7-b65a-0cf580586301
DOI: 10.1101/2020.06.27.174847

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