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Functions of G protein‐coupled receptor 56 in health and disease

12 Aug 2022

Abstract excerpt

Human G protein-coupled receptor 56 (GPR56) is encoded by gene ADGRG1 from chromosome 16q21 and is homologously encoded in mice, at chromosome 8. Both 687 and 693 splice forms are present in humans and mice. GPR56 has a 381 amino acid-long N-terminal extracellular segment and a GPCR proteolysis site upstream from the first transmembrane domain. GPR56 is mainly expressed in the heart, brain, thyroid, platelets,...

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PMID: 35959520
DOI: 10.1111/apha.13866

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