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Article

Rare GPR37L1 Variants Reveal Potential Association between GPR37L1 and Disorders of Anxiety and Migraine.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 8 May 2024

Breitwieser Gerda E, Cippitelli Andrea, Wang Yingcai, Pelletier Oliver, Dershem Ridge, Wei Jianning, Toll Lawrence, Fakhoury Bianca, Brunori Gloria, Metpally Raghu, Carey David J, Robishaw Janet

Abstract excerpt

GPR37L1 is an orphan receptor that couples through heterotrimeric G-proteins to regulate physiological functions. Since its role in humans is not fully defined, we used an unbiased computational approach to assess the clinical significance of rare G-protein-coupled receptor 37-like 1 (GPR37L1) genetic variants found among 51,289 whole-exome sequences from the DiscovEHR cohort. Rare GPR37L1 coding variants were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38569927
DOI: 10.1523/JNEUROSCI.1226-23.2024
PMCID: PMC11089846

Genes

GPR37L1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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