Article

Agmatine accumulation by <i>Pseudomonas aeruginosa</i> clinical isolates confers antibiotic tolerance and dampens host inflammation

2018-04-11

Abstract excerpt

<h4>ABSTRACT</h4> In the cystic fibrosis (CF) airways, Pseudomonas aeruginosa undergoes diverse physiological changes in response to inflammation, antibiotic pressure, oxidative stress and a dynamic bioavailable nutrient pool. These include loss-of-function mutations that result in reduced virulence, altered metabolism and other phenotypes that are thought to confer a selective advantage for long-term persistenc...

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Literature Corpus work: 0966d8be-214c-59de-bac4-6906b0dc7cac
DOI: 10.1101/299099

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