Article

Modulatory effect of Vibrio cholerae toxin co-regulated pilus on mucins, toll-like receptors and NOD genes expression in co-culture model of Caco-2 and Peripheral Blood Mononuclear Cells (PBMC)

2020-04-29

Abstract excerpt

<title>Abstract</title> <p><bold><italic>Background:</italic></bold><italic> Vibrio cholerae, </italic>the causative agent of cholera, as a Gram-negative pathogen tend to colonize the small intestine. The intestinal mucus layer forms mucin physical barrier, consisted from high molecular weight proteins. Regarding the role of toxin–coregulated pilus (TCP) as one of the most important colonization factors of <itali...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 095bd391-371e-53ad-9ead-9c4fd9539956
DOI: 10.21203/rs.3.rs-24597/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Modulatory effect of Vibrio cholerae toxin co-regulated pilus on mucins, toll-like receptors and NOD genes expression in co-culture model of Caco-2 and Peripheral Blood Mononuclear Cells (PBMC)DOI 10.21203/rs.3.rs-24597/v1Read

Helicobacter pylori VacA, a distinct toxin exerts diverse functionalities in numerous cells: An overviewSemantic proximity Read

Characterization of novel alleles of toxin co-regulated pilus A gene (tcpA) from environmental isolates of Vibrio cholerae.Semantic proximity Read

Clostridioides difficile S-Layer Protein A (SlpA) Serves as a General Phage ReceptorSemantic proximity Read

A conserved, immune-regulated peritrophin promotes <i>V. cholerae</i> colonization of the arthropod intestineSemantic proximity Read

Type IV pili are involved in phenotypes associated with Clostridioides difficile pathogenesis.Semantic proximity Read

Development of a Caco-2-based intestinal mucosal model to study intestinal barrier properties and bacteria–mucus interactionsSemantic proximity Read

Identification, annotation of Mucin genes in channel catfish (Ictalurus punctatus) and their expression after bacterial infections revealed by RNA‐Seq analysisSemantic proximity Read

A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in eliciting host bactericidal immune responses to Campylobacter jejuniSemantic proximity Read

Detection of Potential Phytochemicals against ctxAB Toxin to Combat CholeraSemantic proximity Read

Clostridium difficile flagella predominantly activate TLR5-linked NF-κB pathway in epithelial cells.Semantic proximity Read

Delineation of pilin domains required for bacterial association into microcolonies and intestinal colonization by Vibrio cholerae.Semantic proximity Read

Broad Up-Regulation of Innate Defense Factors during Acute CholeraSemantic proximity Read