Article

Detection of Potential Phytochemicals against ctxAB Toxin to Combat Cholera

2024-07-29

Abstract excerpt

Vibrio cholerae is a gram-negative curved rod-shaped bacterium responsible for cholera, an intestinal infection characterized by severe acute watery diarrhea that can be fatal if untreated. The major virulence factor for Vibrio cholerae is cholera toxin ( ctx ), a potent toxin which has two subunits, A and B (ctxAB), that are crucial for the progression of the deadly disease. The B subunit is a pentavalent prote...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b2468d4b-5274-5826-b065-cfe626950b8b
DOI: 10.1101/2024.07.29.605560

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Detection of Potential Phytochemicals against ctxAB Toxin to Combat CholeraDOI 10.1101/2024.07.29.605560Read

Potential use of Sodium Butyrate (SB) as an anti-virulence agent against <i>Vibrio cholerae</i> targeting ToxT virulence proteinSemantic proximity Read

A Systematic Overview of Type II and III Toxin-Antitoxin Systems with a Focus on DruggabilitySemantic proximity Read

Antibiofilm agents with therapeutic potential against enteroaggregative <i>Escherichia coli</i>Semantic proximity Read

Host-derived CEACAM-laden vesicles engage enterotoxigenic <i>E. coli</i> for elimination and toxin neutralizationSemantic proximity Read

Beta-defensin1 derived from Ctenopharyngodon idella exerts anti-Vibrio mimics effects in vitro and in vivo via a multi-target mechanism of actionSemantic proximity Read

<i>Enterocloster citroniae</i> and related gut microbiome species modulate <i>Vibrio cholerae</i> biofilm formation through the production of bioactive small moleculesSemantic proximity Read

Multilevel computational approach to unlock the potential inhibitors of biofilm-EPS, persistence and quinolone signalling in <i>Pseudomonas aeruginosa</i> using mangrove-derived bioactive phytochemicalsSemantic proximity Read

Exploring Computational and Biophysical Tools to Study the Presence of G-Quadruplex Structures: A Promising Therapeutic Solution for Drug-Resistant Vibrio choleraeSemantic proximity Read

Characterization and utility of novel monoclonal antibodies to cholera toxin B subunitSemantic proximity Read

Computational Exploration of Plant Ribosome Inactivating Proteins (RIPs) in Countering Snake Venom: A Novel Therapeutic Opportunity and ChallengesSemantic proximity Read

A new contact killing toxin permeabilizes cells and belongs to a large protein familySemantic proximity Read

Genomic characterization and probiotic potency of Bacillus velezensis CPA1-1 reveals its potential for aquaculture applicationsSemantic proximity Read