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Article

Delineation of pilin domains required for bacterial association into microcolonies and intestinal colonization by Vibrio cholerae.

Molecular microbiology - 1 Feb 2000

Kirn T J, Lafferty M J, Sandoe C M, Taylor R K

Abstract excerpt

The toxin-co-regulated pilus (TCP), a type 4 pilus that is expressed by epidemic strains of Vibrio cholerae O1 and O139, is required for colonization of the human intestine. The TCP structure is assembled as a polymer of repeating subunits of TcpA pilin that form long fibres, which laterally associate into bundles. Previous passive immunization studies have suggested that the C-terminal region of TcpA is exposed...

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Source

Identifiers

PMID: 10692166
DOI: 10.1046/j.1365-2958.2000.01764.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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