Development of a Caco-2-based intestinal mucosal model to study intestinal barrier properties and bacteria–mucus interactions

Abstract excerpt

The intestinal mucosal barrier is a dynamic system that allows nutrient uptake, stimulates healthy microbe–host interactions, and prevents invasion by pathogens. The mucosa consists of epithelial cells connected by cellular junctions that regulate the passage of nutrients covered by a mucus layer that plays an important role in host–microbiome interactions. Mimicking the intestinal mucosa for in vitro assays,...

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