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Article

Type IV pili are involved in phenotypes associated with Clostridioides difficile pathogenesis.

Critical reviews in microbiology - 1 Nov 2024

Ouyang Zirou, Zhao Hanlin, Zhao Min, Yang Yaxuan, Zhao Jianhong

Abstract excerpt

Clostridioides difficile is a Gram-positive, spore-forming, rod-shaped, obligate anaerobe that is the leading cause of antibiotic-associated diarrhea. Type IV pili (T4P) are elongated appendages on the surface of C. difficile that are polymerized from many pilin proteins. T4P play an important role in C. difficile adherence and particularly in its persistence in the host intestine. Recent studies have shown that...

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Identifiers

PMID: 37452617
DOI: 10.1080/1040841X.2023.2235002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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