Article

ROCK1 regulates glycolysis in pancreatic cancer via the c-MYC/PFKFB3 pathway

2024-01-08

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Dysregulation of Rho-associated coiled coil-containing protein kinases (ROCKs) is involved in the metastasis and progression of various malignant tumors. However, how one of the isomers, ROCK1, regulates glycolysis in tumor cells is incompletely understood. Here, we attempted to elucidate how ROCK1 influences pancreatic cancer (PC) progression by regulating glyc...

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Literature Corpus work: 0953d994-9589-5667-ae6a-7549a32d3278
DOI: 10.21203/rs.3.rs-3836816/v1

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