Article

Identification and characterisation of HNF1B as a pro-tumorigenic lineage factor in clear cell renal cell carcinoma

2019-01-01

Abstract excerpt

Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cancer. ccRCCs exhibit considerable genetic intratumour heterogeneity, and current therapies lack long-term efficacy due to drug resistance. Novel therapeutic targets are thus required to combat this disease. The most effective targets are likely to be factors essential for maintaining ccRCC cell phenotypes and survival across all tumour s...

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Literature Corpus work: 093ee896-03f5-554c-8e20-e953b9498b12
DOI: 10.17863/cam.37831

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