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Article

Clear cell renal cell carcinoma ontogeny and mechanisms of lethality.

Nature reviews. Nephrology - 1 Apr 2021

Jonasch Eric, Walker Cheryl Lyn, Rathmell W Kimryn

Abstract excerpt

The molecular features that define clear cell renal cell carcinoma (ccRCC) initiation and progression are being increasingly defined. The TRACERx Renal studies and others that have described the interaction between tumour genomics and remodelling of the tumour microenvironment provide important new insights into the molecular drivers underlying ccRCC ontogeny and progression. Our understanding of common genomic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33144689
DOI: 10.1038/s41581-020-00359-2
PMCID: PMC8172121

Genes

BAP1
PBRM1
VHL

Provenance

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