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Single genome amplification and molecular cloning of HIV-1 populations in acute HIV-1 infection: implications for studies on HIV-1 diversity and evolutionary rate

2025-03-17

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Human immunodeficiency virus type 1 (HIV-1) is one of the fastest evolving human pathogens. Understanding transmission, within-host adaptation, and evolutionary dynamics are pivotal for development of interventions and vaccines. HIV-1 infection is generally caused by one single transmitted founder virus (TFV), and TFV sequences have typically been obtained using single genome...

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Literature Corpus work
092e7aca-c806-599f-ac6e-6f13badb44e7
DOI
10.1101/2025.03.17.25324117
Open publication

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Single genome amplification and molecular cloning of HIV-1 populations in acute HIV-1 infection: implications for studies on HIV-1 diversity and evolutionary rateDOI 10.1101/2025.03.17.25324117
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