Article

Defective HIV DNA genomes provide ancestral relevance critical for phylogenetic inference of reservoir dynamics

2022-05-04

Abstract excerpt

<h4>ABSTRACT</h4> During the course of infection, human immunodeficiency virus (HIV) maintains a stably integrated reservoir of replication-competent viruses within the host genome that are unaffected by antiretroviral therapy. Curative advancements rely heavily on targeting the anatomical reservoirs, though determinants of their evolutionary origins through phyloanatomic inference remain ill-supported through cu...

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Literature Corpus work: fd7354b7-06f5-5f8e-8582-f36c552158be
DOI: 10.1101/2022.05.04.490630

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