Article

Forebrain-specific conditional calcineurin deficiency induces dentate gyrus immaturity and hyper-dopaminergic signaling in mice

2022-09-28

Abstract excerpt

<title>Abstract</title> <p>Calcineurin (Cn), a phosphatase important for synaptic plasticity and neuronal development, has been implicated in the etiology and pathophysiology of neuropsychiatric disorders, including schizophrenia, intellectual disability, autism spectrum disorders, epilepsy, and Alzheimer’s disease. Forebrain-specific conditional Cn knockout mice have been known to exhibit multiple behavioral phe...

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Literature Corpus work: 08fe81ba-9865-56f6-aac6-32dd49a87cc0
DOI: 10.21203/rs.3.rs-2100723/v1

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