Article
Detection of an immature dentate gyrus feature in human schizophrenia/bipolar patients.
Translational psychiatry - 10 Jul 2012
Walton N M, Zhou Y, Kogan J H, Shin R, Webster M, Gross A K, Heusner C L, Chen Q, Miyake S, Tajinda K, Tamura K, Miyakawa T, Matsumoto M
Abstract excerpt
Hippocampus-associated cognitive impairments are a common, highly conserved symptom of both schizophrenia (SCZ) and bipolar disorder (BPD). Although the hippocampus is likely an impacted region in SCZ/BPD patients, the molecular and cellular underpinnings of these impairments are difficult to identify. An emerging class of mouse models for these psychiatric diseases display similar cognitive impairments to those...
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