Article

BayesRB: a markov chain Monte Carlo-based polygenic genetic risk score algorithm for dichotomous traits

2022-03-02

Abstract excerpt

<h4> A bstract </h4> Identifying high-risk individuals with diseases through reliable prediction models guides screening and preventive treatment. Most complex diseases have a genetic basis influenced by multiple genes and so disease risk can be estimated using polygenic risk score (PRS) algorithms. Many PRS algorithms have been developed so far. Among them, BayesR shows good characteristics of unbiasedness, ac...

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Literature Corpus work: 08f67d3d-fbe0-5cd4-92f8-757f2ac3908d
DOI: 10.1101/2022.02.27.482193

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