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Article

A probabilistic method for identifying rare variants underlying complex traits.

BMC genomics - 1 Jan 2013

Wang Jiayin, Zhao Zhongmeng, Cao Zhi, Yang Aiyuan, Zhang Jin

Abstract excerpt

BACKGROUND: Identifying the genetic variants that contribute to disease susceptibilities is important both for developing methodologies and for studying complex diseases in molecular biology. It has been demonstrated that the spectrum of minor allelic frequencies (MAFs) of risk genetic variants ranges from common to rare. Although association studies are shifting to incorporate rare variants (RVs) affecting...

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PMID: 23369113
DOI: 10.1186/1471-2164-14-S1-S11
PMCID: PMC3549819

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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