Article

<i>In vivo</i> measurements reveal a single 5’ intron is sufficient to increase protein expression level in <i>C. elegans</i>

2018-12-17

Abstract excerpt

Introns can increase gene expression levels using a variety of mechanisms collectively referred to as Intron Mediated Enhancement (IME). To date, the magnitude of IME has been quantified in human cell culture and plant models by comparing intronless reporter gene expression levels to those of intron-bearing reporter genes in vitro (mRNA, Western Blots, protein activity), using genome editing technologies that lac...

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Literature Corpus work: 08e8168e-0887-5bfa-9a14-0cffb3fe4fa9
DOI: 10.1101/499459

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