Article

Spatially coherent diffusion of human RNA Pol II depends on transcriptional state rather than chromatin motion

2022-01-21

Abstract excerpt

Gene transcription by RNA polymerase II (RNAP II) is a tightly regulated process in the genomic, temporal, and spatial context. Transcriptionally active genes often spatially cluster at RNA Pol II foci, called transcription factories, causing long-range interactions between distal sites of the genome. Recently, we have shown that chromatin exhibits spatially long-range coherently moving regions over the entire nuc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 08e56c38-1d43-5b9d-a137-172811c4af07
DOI: 10.1101/2022.01.19.476954

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Spatially coherent diffusion of human RNA Pol II depends on transcriptional state rather than chromatin motionDOI 10.1101/2022.01.19.476954Read

Formation of correlated chromatin domains at nanoscale dynamic resolution during transcriptionSemantic proximity Read

Synthetic analysis of chromatin tracing and live-cell imaging indicates pervasive spatial coupling between genesSemantic proximity Read

Cell Cycle-Dependent Chromatin Motion: A Role for DNA Content Doubling Over CohesionSemantic proximity Read

Structured illumination to spatially map chromatin motionsSemantic proximity Read

FreeTrace enables fractional Brownian motion-based single-molecule tracking and robust anomalous diffusion analysisSemantic proximity Read

Liquid-like transcription condensates locally constrain chromatin in living human cellsSemantic proximity Read

Dynamic Nucleosome Movement Provides Structural Information of Topological Chromatin Domains in Living Human CellsSemantic proximity Read

Cluster size determines internal structure of transcription factories in human cellsSemantic proximity Read

Transcriptional activity generates chromatin motion that drives nuclear blebbingSemantic proximity Read

Real-time chromatin dynamics at the single gene level during transcription activationSemantic proximity Read

Phase Separation and Correlated Motions in Motorized GenomeSemantic proximity Read

Principles of transcription factor traffic on folded chromatinSemantic proximity Read