Article

Phase Separation and Correlated Motions in Motorized Genome

2022-05-10

Abstract excerpt

The human genome is arranged in the cell nucleus non-randomly, and phase separation has been proposed as an important driving force for genome organization. However, the cell nucleus is an active system, and the contribution of non-equilibrium activities to phase separation and genome structure and dynamics remains to be explored. We simulated the genome using an energy function parameterized with chromosome confo...

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Literature Corpus work: ede1d301-1053-5967-8753-1cb69e189092
DOI: 10.1101/2022.05.10.491350

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