Article

Lipopolysaccharide Induces Trained Innate Immune Tolerance in the Heart Through Interferon Signaling in a Model of Stress-Induced Cardiomyopathy

2024-09-26

Abstract excerpt

<h4>Background</h4> Although the ability of the heart to adapt to environmental stress has been studied extensively, the molecular and cellular mechanisms responsible for cardioprotection are not yet fully understood. <h4>Methods</h4> We administered Toll-like receptor (TLR) agonists or a diluent to wild-type mice and assessed their potential to induce cardiac protection against injury from a high intraperitonea...

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Literature Corpus work: 08b46187-248f-53c7-9596-b75f32e718c6
DOI: 10.1101/2024.09.24.614798

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