Article

Cross-species single-cell comparison of systemic and cardiac inflammatory responses after cardiac injury

2023-03-16

Abstract excerpt

The immune system coordinates the response to cardiac injury and is known to control regenerative and fibrotic scar outcomes in the heart and subsequent chronic low-grade inflammation associated with heart failure. Here we profiled the inflammatory response to heart injury using single cell transcriptomics to compare and contrast two experimental models with disparate outcomes. We used adult mice, which like human...

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Identifiers and source

Literature Corpus work: d1992420-df03-5d60-80bf-abcaee128556
DOI: 10.1101/2023.03.15.532865

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