Article

Cell-type-specific efferocytosis determines functional plasticity of alveolar macrophages

2023-03-07

Abstract excerpt

Resolution of lung injuries is vital to maintain gas exchange. Concurrently, there is an increased risk of secondary bacterial infections. Alveolar macrophages (AMs) are crucial to clear bacteria and control initiation and resolution of inflammation, but environmental cues that switch functional phenotypes of AMs remain elusive. Here, we discovered an incapacity of AMs to mount an effective immune response to bact...

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Literature Corpus work: 08842869-1aee-5815-8071-4e0719ff54e9
DOI: 10.1101/2023.03.07.528464

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