Article
Efferocytosis and lung disease.
Chest - 1 Jun 2013
McCubbrey Alexandra L, Curtis Jeffrey L
Abstract excerpt
In healthy individuals, billions of cells die by apoptosis each day. Clearance of these apoptotic cells, termed "efferocytosis," must be efficient to prevent secondary necrosis and the release of proinflammatory cell contents that disrupt tissue homeostasis and potentially foster autoimmunity. During inflammation, most apoptotic cells are cleared by macrophages; the efferocytic process actively induces a...
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