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Novel antiviral interferon sensitive genes unveiled by correlation-driven gene selection and integrated systems biology approaches

2021-04-06

Abstract excerpt

Interferons (IFNs) are key cytokines involved in alerting the immune system to viral infection. After IFN stimulation, cellular transcriptional profile critically changes, leading to the expression of several IFN stimulated genes (ISGs) that exert a wide variety of antiviral activities. Despite many ISGs have been already identified, a comprehensive network of coding and non-coding genes with a central role in IFN...

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Literature Corpus work
08800dea-a1dd-59c0-b034-5699b372a181
DOI
10.1101/2021.04.05.438481
Open publication

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Novel antiviral interferon sensitive genes unveiled by correlation-driven gene selection and integrated systems biology approachesDOI 10.1101/2021.04.05.438481
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