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Systems Biology of Interferon Responses

1 Jan 2011

Abstract excerpt

The interferons (IFNs) are a pleiotropic family of cytokines that perform fundamental functions in protecting host organisms from disease and in maintaining homeostasis. Like other multifunctional cytokines, excessive or inappropriate activity can cause toxicity and even death. Therefore, host organisms have evolved specific and highly regulated mechanisms to control the temporal and tissue specificity of...

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PMID: 21226606
DOI: 10.1089/jir.2010.0126

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