Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hepatic gene expression and prediction of therapy response in chronic hepatitis C patients.

Journal of hepatology - 1 May 2008

Selzner Nazia, Chen Limin, Borozan Ivan, Edwards Aled, Heathcote E Jenny, McGilvray Ian

Abstract excerpt

Chronic hepatitis C (HCV) infection remains a major health problem worldwide. The current standard of care is a combination of pegylated interferon-alpha and ribavirin. Considering the length of antiviral therapy, as well as its side effects and costs, accurate prediction of treatment response prior to initiation of treatment is critical. In addition to viral, demographic and environmental factors, host genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Expression Profiling
Share to Genomics
Share to Hepatitis C, Chronic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 18329749
DOI: 10.1016/j.jhep.2008.02.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hepatic gene expression and prediction of therapy response in chronic hepatitis C patients.PMID 18329749Read ↗

Hepatic Gene Expression Discriminates Responders and Nonresponders in Treatment of Chronic Hepatitis C Viral InfectionSemantic proximity Read ↗

Liver Gene Expression Profiles Correlate with Virus Infection and Response to Interferon Therapy in Chronic Hepatitis B PatientsSemantic proximity Read ↗

Genetics, Genomics, and Proteomics: Implications for the Diagnosis and the Treatment of Chronic Hepatitis CSemantic proximity Read ↗

Genomics and HCV infection: progression of fibrosis and treatment response.Semantic proximity Read ↗

Gene Expression Patterns That Correlate With Hepatitis C and Early Progression to Fibrosis in Liver Transplant RecipientsSemantic proximity Read ↗

Novel antiviral interferon sensitive genes unveiled by correlation-driven gene selection and integrated systems biology approachesSemantic proximity Read ↗

Interferon-induced gene expression is a stronger predictor of treatment response than IL28B genotype in patients with hepatitis C.Semantic proximity Read ↗

Dynamics of PBMC gene expression in hepatitis C virus genotype 1-infected patients during combined peginterferon/ribavirin therapy.Semantic proximity Read ↗

Interferon stimulated genes and hepatitis C virus infection.Semantic proximity Read ↗

The Interferon Signaling Pathway Genes as Biomarkers of Hepatitis C Virus Disease Progression and Response to TreatmentSemantic proximity Read ↗

Hepatic gene expression during treatment with peginterferon and ribavirin: Identifying molecular pathways for treatment responseSemantic proximity Read ↗

Early gene expression profiles of patients with chronic hepatitis C treated with pegylated interferon‐alfa and ribavirin†Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.