Article

Defining the Characteristics of Type I Interferon Stimulated Genes: Insight from Expression Data and Machine Learning

2021-10-09

Abstract excerpt

A virus-infected cell triggers a signalling cascade resulting in the secretion of interferons (IFNs), which in turn induce the up-regulation of IFN-stimulated genes (ISGs) that play an important role in the inhibition of the viral infection and the return to cellular homeostasis. Here, we conduct detailed analyses on 7443 features relating to evolutionary conservation, nucleotide composition, gene expression, amin...

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Literature Corpus work: cd5a760a-e874-5a7d-8a63-670054651b8a
DOI: 10.1101/2021.10.08.463622

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