Article

Landscape of cancer associated EpCAM mutations: molecular modeling, Predictive Insights and Impact on Patient Survival

2025-03-12

Abstract excerpt

<title>Abstract</title> <p>Background EpCAM (epithelial cell adhesion molecule) is a key regulator of epithelial cell-cell adhesion, signal transduction, tissue regeneration, and serves as a stem cell marker. It is frequently overexpressed in epithelial cancers and is linked to tumor progression, survival, and metastasis. However, the functional impact of EpCAM mutations in cancer remains poorly understood. Meth...

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Literature Corpus work: 086b505c-4759-53c5-bd25-397660223a3c
DOI: 10.21203/rs.3.rs-6174915/v1

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