Article
Alterations in protein kinase networks in astrocytes and neurons derived from patients with familial Alzheimer’s Disease
2022-06-17
Abstract excerpt
Neurons and astrocytes derived from Alzheimer’s Disease (AD) patient induced pluripotent stem cells are an evolving technology used to study the pathogenesis and etiology of AD. As the utility of mouse models of AD are increasingly coming into questions, using iPSC technology may offer an opportunity to study this disease with human substrates. Herein, we using a hypothesis generating platform, the PamGene12 Kinom...
Topics
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- Alzheimer's disease research and treatments
- Amyotrophic Lateral Sclerosis Research
- Biochemical Acid Research Studies
- Cancer-related cognitive impairment studies
- Histone Deacetylase Inhibitors Research
- Mitochondrial Function and Pathology
- Neuroinflammation and Neurodegeneration Mechanisms
- Tryptophan and brain disorders
Identifiers and source
- Literature Corpus work
- 0868e805-8639-5656-bef1-8677d7f61b2c
- DOI
- 10.1101/2022.06.14.496149
