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The multifaceted role of kinases in amyotrophic lateral sclerosis: genetic, pathological and therapeutic implications

9 Mar 2020

Abstract excerpt

Amyotrophic lateral sclerosis is the most common degenerative disorder of motor neurons in adults. As there is no cure, thousands of individuals who are alive at present will succumb to the disease. In recent years, numerous causative genes and risk factors for amyotrophic lateral sclerosis have been identified. Several of the recently identified genes encode kinases. In addition, the hypothesis that...

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PMID: 32206784
DOI: 10.1093/brain/awaa022

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