Article

Hepatocyte high-mobility group box 1 protects against steatosis and cellular stress during high fat diet feeding

2020-10-19

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Circulating high-mobility group box 1 (HMGB1) plays important roles in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). Intracellular HMGB1 is critical for the biology of hepatocytes. However, the intracellular role of HMGB1 in hepatocellular steatosis is unknown. Therefore, we aimed to investigate the role of hepatocyte-specific HMGB1 (HC-HMGB1) in...

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Literature Corpus work: 084b96c8-13d3-5ff1-a724-91e2b1b89d23
DOI: 10.21203/rs.3.rs-30696/v3

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