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Article

SREBP Regulation of Lipid Metabolism in Liver Disease, and Therapeutic Strategies

2023-10-31

Abstract excerpt

Sterol regulatory element-binding proteins (SREBPs) are transcription factors that regulate genes involved in the biogenesis of cholesterol, fatty acids, and triglycerides. SREBPs are involved in the pathogenesis of non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), fibrosis, and hepatocellular carcinoma (HCC). We review the mechanisms by which SREBPs regulate lipogenesis, the alterat...

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Literature Corpus work
0bbdd69a-5f4a-5c6c-86c6-a6b0a513a8e2
DOI
10.20944/preprints202310.2022.v1
Open publication

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SREBP Regulation of Lipid Metabolism in Liver Disease, and Therapeutic StrategiesDOI 10.20944/preprints202310.2022.v1
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