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Emerging Roles of High-mobility Group Box-1 in Liver Disease

21 Oct 2024

Abstract excerpt

High-mobility group box-1 (HMGB1) is an architectural chromosomal protein with various roles depending on its cellular localization. Extracellular HMGB1 functions as a prototypical damage-associated molecular pattern that triggers inflammation and adaptive immune responses, mediated by specific cell surface receptors, including receptors for advanced glycation end products and toll-like receptors....

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Liver Disease and Transplantation
Liver Disease Diagnosis and Treatment
Liver physiology and pathology

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39649031
DOI: 10.14218/jcth.2024.00317

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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