Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Emerging Roles of High-mobility Group Box-1 in Liver Disease

21 Oct 2024

Abstract excerpt

High-mobility group box-1 (HMGB1) is an architectural chromosomal protein with various roles depending on its cellular localization. Extracellular HMGB1 functions as a prototypical damage-associated molecular pattern that triggers inflammation and adaptive immune responses, mediated by specific cell surface receptors, including receptors for advanced glycation end products and toll-like receptors....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Liver Disease and Transplantation
Share to Liver Disease Diagnosis and Treatment
Share to Liver physiology and pathology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39649031
DOI: 10.14218/jcth.2024.00317

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Emerging Roles of High-mobility Group Box-1 in Liver DiseasePMID 39649031Read ↗

HMGB1: An overview of its roles in the pathogenesis of liver diseaseSemantic proximity Read ↗

Emerging Role of High-Mobility Group Box 1 (HMGB1) in Liver DiseasesSemantic proximity Read ↗

High Mobility Group Box 1 (HMGB1): Molecular Signaling and Potential Therapeutic StrategiesSemantic proximity Read ↗

Emerging roles for HMGB1 protein in immunity, inflammation, and cancerSemantic proximity Read ↗

High mobility group box 1 (HMGB1): a pivotal regulator of hematopoietic malignanciesSemantic proximity Read ↗

The dual role and therapeutic potential of high-mobility group box 1 in cancerSemantic proximity Read ↗

Role of HMGB1 and its associated signaling pathways in human malignanciesSemantic proximity Read ↗

Multiple functions of HMGB1 in cancerSemantic proximity Read ↗

Nuclear HMGB1 protects from nonalcoholic fatty liver disease through negative regulation of liver X receptorSemantic proximity Read ↗

Masquerader: High Mobility Group Box-1 and CancerSemantic proximity Read ↗

Nuclear HMGB1 protects from non-alcoholic fatty liver diseases through negative regulation of liver X receptorSemantic proximity Read ↗

Hepatocyte high-mobility group box 1 protects against steatosis and cellular stress during high fat diet feedingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.