Article

Disruption of Redox Homeostasis by Enzymatic Activation of a Triakylphosphine Probe in Mitochondria

2019-08-30

Abstract excerpt

Redox homeostasis is essential for cell function and its disruption is associated with cancer, metabolic and neurodegenerative diseases. Redox balance is largely regulated by the relative concentrations of reduced and oxidized glutathione. In eukaryotes, this ratio is different in each cell compartment, and disruption of the mitochondrial redox balance has been specifically linked to pathologies such as obesity an...

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Literature Corpus work: 081f3ce9-a45a-545b-ae3e-05c0b8ac0787
DOI: 10.26434/chemrxiv.9741983.v1

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