Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Imaging dynamic redox changes in mammalian cells with green fluorescent protein indicators.

The Journal of biological chemistry - 21 May 2004

Dooley Colette T, Dore Timothy M, Hanson George T, Jackson W Coyt, Remington S James, Tsien Roger Y

Abstract excerpt

Changes in the redox equilibrium of cells influence a host of cell functions. Alterations in the redox equilibrium are precipitated by changing either the glutathione/glutathione-disulfide ratio (GSH/GSSG) and/or the reduced/oxidized thioredoxin ratio. Redox-sensitive green fluorescent proteins (GFP) allow real time visualization of the oxidation state of the indicator. Ratios of fluorescence from excitation at...

Topics

Join the communities discussing this publication.

Epidermal Growth Factor
Glutathione
HL-60 Cells
Hypoxia
Lysophospholipids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Xanthine Oxidase

Source

Identifiers

PMID: 14985369
DOI: 10.1074/jbc.M312847200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Imaging dynamic redox changes in mammalian cells with green fluorescent protein indicators.PMID 14985369Read ↗

Investigating mitochondrial redox potential with redox-sensitive green fluorescent protein indicators.Semantic proximity Read ↗

Real-time redox adaptations in human airway epithelial cells exposed to isoprene hydroxy hydroperoxideSemantic proximity Read ↗

Monitoring oxidative stress and DNA damage induced by heavy metals in yeast expressing a redox-sensitive green fluorescent protein.Semantic proximity Read ↗

Disruption of Redox Homeostasis by Enzymatic Activation of a Triakylphosphine Probe in MitochondriaSemantic proximity Read ↗

Modulating Protein Function through Genetically Encoded Oxidative ChemistrySemantic proximity Read ↗

Measuring intracellular redox conditions using GFP-based sensors.Semantic proximity Read ↗

A genome-wide screen in yeast identifies specific oxidative stress genes required for the maintenance of sub-cellular redox homeostasis.Semantic proximity Read ↗

Ultra-fast genetically encoded sensor for precise real-time monitoring of physiological and pathophysiological peroxide dynamicsSemantic proximity Read ↗

A High-Performance Genetically Encoded Fluorescent Biosensor for Imaging Physiological PeroxynitriteSemantic proximity Read ↗

Flow Cytometry of Oxygen and Oxygen-Related Cellular StressSemantic proximity Read ↗

Determination of the in vivo redox potential by one-wavelength spectro-microscopy of roGFP.Semantic proximity Read ↗

Structure-guided engineering of a fast genetically encoded sensor for real-time H <sub>2</sub> O <sub>2</sub> monitoringSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.