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Article

Imaging dynamic redox changes in mammalian cells with green fluorescent protein indicators.

The Journal of biological chemistry - 21 May 2004

Dooley Colette T, Dore Timothy M, Hanson George T, Jackson W Coyt, Remington S James, Tsien Roger Y

Abstract excerpt

Changes in the redox equilibrium of cells influence a host of cell functions. Alterations in the redox equilibrium are precipitated by changing either the glutathione/glutathione-disulfide ratio (GSH/GSSG) and/or the reduced/oxidized thioredoxin ratio. Redox-sensitive green fluorescent proteins (GFP) allow real time visualization of the oxidation state of the indicator. Ratios of fluorescence from excitation at...

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PMID: 14985369
DOI: 10.1074/jbc.M312847200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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