Article

Systemic extracellular acidification is a hallmark of aging

2024-09-26

Abstract excerpt

Understanding the critical pathophysiological processes that promote age-related disease is needed to uncover effective targets for preventive medicine. Here, we investigate how extracellular pH changes with age and its impact on longevity, using fly and mouse models. We find that extracellular acidification occurs in flies during aging and correlates to mortality rate. With age, flies also become more susceptible...

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Identifiers and source

Literature Corpus work: 07fcec2d-47a1-5e4e-8d08-dea41f7760af
DOI: 10.1101/2024.09.24.614672

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