Article

Machine learning identifies novel signatures of antifungal drug resistance in <i>Saccharomycotina</i> yeasts

2025-05-10

Abstract excerpt

Antifungal drug resistance is a major challenge in fungal infection management. Numerous genomic changes are known to contribute to acquired drug resistance in clinical isolates of specific pathogens, but whether they broadly explain natural resistance across entire lineages is unknown. We leveraged genomic, ecological, and phenotypic trait data from naturally sampled strains from nearly all known species in subph...

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Literature Corpus work: 07f96800-9d1c-5bfd-b832-cf11057c41a7
DOI: 10.1101/2025.05.09.653161

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