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Investigating role of positively selected genes and mutation sites of ERG11 in drug resistance of Candida albicans.

Archives of microbiology - 18 Oct 2024

Fandilolu Prayagraj, Kumar Chandan, Palia Dushyant, Idicula-Thomas Susan

Abstract excerpt

The steep increase in acquired drug resistance in Candida isolates has posed a great challenge in the clinical management of candidiasis globally. Information of genes and codon sites that are positively selected during evolution can provide insights into the mechanisms driving antifungal resistance in Candida. This study aimed to create a manually curated list of genes of Candida spp. reported to be associated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39422772
DOI: 10.1007/s00203-024-04159-1

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