Article

Genetic variation and gene expression across multiple tissues and developmental stages in a non-human primate

2016-12-09

Abstract excerpt

By analyzing multi-tissue gene expression and genome-wide genetic variation data in samples from a vervet monkey pedigree, we generated a transcriptome resource and produced the first catalogue of expression quantitative trait loci (eQTLs) in a non-human primate model. This catalogue contains more genome-wide significant eQTLs, per sample, than comparable human resources, and reveals sex and age-related expression...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 07c87a52-187e-5c37-91ce-4329f4bce254
DOI: 10.1101/092874

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetic variation and gene expression across multiple tissues and developmental stages in a non-human primateDOI 10.1101/092874Read

Genetic variation and gene expression across multiple tissues and developmental stages in a nonhuman primate.Semantic proximity Read

A single-cell multi-omic atlas spanning the adult rhesus macaque brainSemantic proximity Read

Resources for functional genomic studies of health and development in nonhuman primates.Semantic proximity Read

Evolutionary and biomedical implications of sex differences in the primate brain transcriptomeSemantic proximity Read

Single-cell-resolution transcriptome map of human, chimpanzee, bonobo, and macaque brainsSemantic proximity Read

Frequent functional orthology of long noncoding RNAs and genomic loci associated with complex traits and disordersSemantic proximity Read

A non-human primate system for large-scale genetic studies of complex traits.Semantic proximity Read

Whole-Genome and RNA Sequencing Reveal Variation and Transcriptomic Coordination in the Developing Human Prefrontal Cortex.Semantic proximity Read

Evolution of regulatory signatures in primate cortical neurons at cell type resolutionSemantic proximity Read

The human and non-human primate developmental GTEx projects.Semantic proximity Read

Cell-type-specific cis-eQTLs in eight human brain cell types identify novel risk genes for psychiatric and neurological disorders.Semantic proximity Read

A comparison of gene expression and DNA methylation patterns across tissues and speciesSemantic proximity Read