Article
A non-human primate system for large-scale genetic studies of complex traits.
Human molecular genetics - 1 Aug 2012
Jasinska Anna J, Lin Michelle K, Service Susan, Choi Oi-Wa, DeYoung Joseph, Grujic Olivera, Kong Sit-Yee, Jung Yoon, Jorgensen Mathew J, Fairbanks Lynn A, Turner Trudy, Cantor Rita M, Wasserscheid Jessica, Dewar Ken, Warren Wesley, Wilson Richard K, Weinstock George, Jentsch J David, Freimer Nelson B
Abstract excerpt
Non-human primates provide genetic model systems biologically intermediate between humans and other mammalian model organisms. Populations of Caribbean vervet monkeys (Chlorocebus aethiops sabaeus) are genetically homogeneous and large enough to permit well-powered genetic mapping studies of quantitative traits relevant to human health, including expression quantitative trait loci (eQTL). Previous...
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