Article

Multi-omics comprehensive analysis of renal clear cell carcinoma to distinguish subtypes with different molecular characterizations and therapeutic strategies

2023-07-24

Abstract excerpt

<h4>Purpose: </h4> Kidney renal clear cell carcinoma (KIRC) is the most prevalent heterogeneous subtype of malignant renal cell carcinoma and is well known as a common genitourinary cancer. Stratifying tumors based on heterogeneity is essential for better treatment options. Methods In this study, consensus clusters were constructed based on gene expression, DNA methylation, and gene mutation data, which were comb...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 94f83420-6b95-583b-9838-e85fd09fa897
DOI: 10.21203/rs.3.rs-3182826/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Multi-omics comprehensive analysis of renal clear cell carcinoma to distinguish subtypes with different molecular characterizations and therapeutic strategiesDOI 10.21203/rs.3.rs-3182826/v1Read

Comprehensive characterization of immune- and inflammation-associated biomarkers based on multi-omics integration in kidney renal clear cell carcinomaSemantic proximity Read

Based on the identification of tumor antigens and immune subtypes in renal clear cell carcinoma for mRNA vaccine developmentSemantic proximity Read

Integrative Bioinformatics and In Vitro Exploration of EVI2A Expression: Unraveling its Immunological and Prognostic Implications in Kidney Renal Clear Cell CarcinomaSemantic proximity Read

A Newly Defined m7G-Related Gene Signature for Overall Survival Prognosis of Kidney Renal Clear Cell CarcinomaSemantic proximity Read

Development of a Prognostic Index for Clear Cell Renal Cell Carcinoma Using Machine Learning and Multi-omics Analysis to Enhance Clinical Outcomes and Drug SensitivitySemantic proximity Read

Molecular Signature Of Subtypes Of Renal Cell Carcinomas And Immunotherapy StrategySemantic proximity Read

Combination of bulk RNA sequencing and scRNA sequencing uncover the molecular characteristics of MAPK signaling in kidney renal clear cell carcinomaSemantic proximity Read

Identification of genes and pathways involved in kidney renal clear cell carcinomaSemantic proximity Read

Predictive value of m1A-related genes in kidney renal clear cell carcinomaSemantic proximity Read

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell CarcinomaSemantic proximity Read

A Novel Gene Signature of Tripartite Motif Family for Predicting the Prognosis in Kidney Renal Clear Cell Carcinoma and Its Association With Immune Cell InfiltrationSemantic proximity Read

NOTCH4 Predicts the Prognosis and Is Associated with Immune Infiltration in Kidney Renal Clear Cell CarcinomaSemantic proximity Read