Article

ARHGEF26 enhances <i>Salmonella</i> invasion and inflammation in cells and mice

2020-12-30

Abstract excerpt

Salmonella hijack host machinery in order to invade cells and establish infection. While considerable work has described the role of host proteins in invasion, much less is known regarding how natural variation in these invasion-associated host proteins affects Salmonella pathogenesis. Here we leveraged a candidate cellular GWAS screen to identify natural genetic variation in the ARHGEF26 (Rho Guanine Nucleotide...

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Literature Corpus work: 0757ea32-fdf4-57d4-a8ed-4698eaee0e9a
DOI: 10.1101/2020.12.30.424811

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