Article

The interaction of enteric bacterial effectors with the host engulfment pathway control innate immune responses

2021-06-07

Abstract excerpt

<h4>Background</h4> Host engulfment protein ELMO1 generates intestinal inflammation following internalization of enteric bacteria. In Shigella , bacterial effector IpgB1 interacts with ELMO1 and promotes bacterial invasion. IpgB1 belongs to the WxxxE effector family, a motif found in several effector of enteric pathogens. Here, we have studied the role of WxxxE effectors, with emphasis on Salmonella SifA and wh...

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Literature Corpus work: f4923144-6daa-58c6-989d-ab292c1be0c3
DOI: 10.1101/2021.06.07.447447

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