Article
Salmonella Activation of STAT3 Signaling by SarA Effector Promotes Intracellular Replication and Production of IL-10.
Cell reports - 19 Jun 2018
Jaslow Sarah L, Gibbs Kyle D, Fricke W Florian, Wang Liuyang, Pittman Kelly J, Mammel Mark K, Thaden Joshua T, Fowler Vance G, Hammer Gianna E, Elfenbein Johanna R, Ko Dennis C
Abstract excerpt
Salmonella enterica is an important foodborne pathogen that uses secreted effector proteins to manipulate host pathways to facilitate survival and dissemination. Different S. enterica serovars cause disease syndromes ranging from gastroenteritis to typhoid fever and vary in their effector repertoire. We leveraged this natural diversity to identify stm2585, here designated sarA (Salmonella anti-inflammatory...
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