Article

A luminal proteome of the endoplasmic reticulum and Golgi apparatus reveals a novel modulator of ER stress tolerance in African trypanosomes

2026-04-06

Abstract excerpt

<h4>ABSTRACT</h4> African trypanosomes employ specialised mechanisms of membrane trafficking as a key strategy to persist in both the mammalian host and insect vector. Their survival and pathogenicity rely on the continuous synthesis and surface delivery of extremely abundant surface coat proteins, imposing an extraordinary biosynthetic burden on the secretory pathway. Despite this, the luminal proteome of the T...

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Literature Corpus work: 8234be5e-abf8-5b79-99ad-714a0d1bf453
DOI: 10.64898/2026.04.03.716285

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