Article

Endogenous TOM20 Proximity Labelling: A Swiss-Knife for the Study of Mitochondrial Proteins in Human Cells

2023-04-21

Abstract excerpt

Biotin-based proximity labeling approaches, such as BioID, have demonstrated their use for the study of mitochondria proteomes in living cells. The use of genetically engineered BioID cell lines enables the detailed characterization of poorly characterized processes such as mitochondrial co-translational import. In this process, translation is coupled to the translocation of the mitochon-drial proteins, alleviatin...

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Literature Corpus work: 24932755-e368-5e32-a9a1-2ecfe2fd839f
DOI: 10.20944/preprints202212.0304.v2

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